Repligen线上技术研讨会回顾：基因治疗2.0 - 行之有效的生产解决方案
基因治疗2.0：行之有效的解决方案
鉴于基于病毒载体的基因治疗数量和类型的激增，行业需要显著提高其生产效率达10至100倍以上，才能满足每年增长的需求。 对于产能的短缺，光靠新建工厂已不足以提供一个完整的解决方案。
Repligen在线技术研讨会回顾了行业技术变革的主要驱动因素，从先进技术的早期采纳者学习，评估风险，并合作设定基因治疗制造2.0标准。主题包括病毒载体生产的上游强化、收获澄清、层析、UF/DF以及分析。
Welcome to Gene Therapy 2.0: Manufacturing Solutions that Work
欢迎进入线上技术研讨会基因治疗2.0：行之有效的解决方案
Vikas Gupta, VP & GM, Downstream Processing and Gene Therapy, Repligen
Current challenges and limitations in Gene Therapy manufacturing
当前基因治疗生产的挑战和限制
Plenary speaker: Matthias Hebben, PhD, Global Vice President and Head of Technology, LogicBio Therapeutics
Increasing lentivirus vector bioreactor yield with simplified execution using tangential flow depth filtration
通过切向流深层过滤的简单执行，提高慢病毒载体生物反应器产量
Michael Bransby, Research and Development Direct of Process Technology, Repligen
AAV viral vector process development and clinical production: Automated TFF scale-up, scale-down and process characterization using KrosFlo® TFF Systems
AAV病毒载体工艺开发和临床生产：使用KrosFlo® TFF系统实现自动化TFF规模放大、规模缩小以及工艺表征
Dr. George Buchman, Vice President of Pre-Clinical and Process Development, Catalent Biosciences
Allowing the process to determine filtration technology: hollow fiber vs. flat sheet
让工艺确定过滤技术：中空纤维 vs. 平板膜包
Jason Rodrigues, Senior Manufacturing Engineer, Genopis
Determination of bacterial growth curve using OD600 and SoloVPE® Device
使用OD600和SoloVPE®确定细菌生长曲线
Dr. Tanja Buch, Technical Director, BioFactory Competence Center
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Repligen Corporation
41 Seyon Street, Building 1, Suite 100, Waltham, MA, 02453, USA
phone: 781. 250. 0111
Fax: 781. 250. 0115
Web: www.repligen.com
瑞普利金（上海）生物科技有限公司
中国（上海）自由贸易试验区张江路1238弄恒越国际大厦1号2层G座
电话：021 - 6881 0228
网站：cn.repligen.com
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